San Antonio Spurs at Los Angeles Lakers odds, picks and predictions – USA TODAY Sportsbook Wire

The San Antonio Spurs (14-33) and Los Angeles Lakers (22-26) meet Wednesday at Crypto.com Arena. Tip-off is scheduled for 10:30 p.m. ET. Below, we analyze Tipico Sportsbook’s lines around the Spurs vs. Lakers odds, and make our expert NBA picks and predictions.

The Spurs failed to cover the spread as 8-point underdogs Monday in a 147-127 loss at the Portland Trail Blazers. F Keldon Johnson scored a team-high 20 points as San Antonio lost for the 7th time in 8 games. The Spurs are 6-4 against the spread (ATS) in their last 10 games after losing by 20 or more points in their previous contest.

The Lakers failed to cover as 4.5-point underdogs Tuesday in a 133-115 loss vs. the Los Angeles Clippers. F LeBron James finished with 46 points and 9 made 3-pointers, both game-highs, as the Lakers failed to capitalize after winning back-to-back games, sitting 13th in the Western Conference. The Lakers are 14-2 ATS in their last 16 games vs. teams with a losing record.

Anthony Davis (foot) is expected to return to the lineup Wednesday after missing 20 games and newly acquired F Rui Hachimura will reportedly be available to play.

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Spurs at Lakers odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 3:25 p.m. ET.

  • Moneyline (ML): Spurs +210 (bet $100 to win $210) | Lakers -250 (bet $250 to win $100)
  • Against the spread (ATS): Spurs +6.5 (-108) | Lakers -6.5 (-112)
  • Over/Under (O/U): 243.5 (O: -110 | U: -110)

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Spurs at Lakers key injuries

Spurs

  • Romeo Langford (hip) questionable
  • Devin Vassell (knee) out

Lakers

  • Not yet submitted

For most recent updates: Official NBA injury report.

Spurs at Lakers picks and predictions

Prediction

Lakers 130, Spurs 119

Moneyline

PASS.

The Lakers (-250) should win, but there is no need to risk more than 2 times your potential profit on the moneyline when Los Angeles should win by margin. Bet the spread or total instead.

Against the spread

BET LAKERS -6.5 (-112).

Stars returning from injury can sometimes disrupt team chemistry, but Davis is familiar enough with the Lakers that the 8-time All-Star should instantly make Los Angeles better. The league saw a similar situation last Wednesday when G Bradley Beal returned to Washington and the Wizards guard has since led his team to 3 straight wins and covers. Los Angeles is 3-0 ATS vs. the Spurs this season and the addition of Davis should help the Lakers cover for a 4th consecutive meeting. Lay the points.

Over/Under

BET OVER 243.5 (-110).

The Over is 8-0-1 in San Antonio’s last 9 road games vs. teams with a winning record at home and 7-1 in Los Angeles’ last 8 games following a loss by more than 10 points in their previous contest. These teams play high-scoring games vs. each other in Los Angeles as the Over is 9-3-1 in the last 13 meetings and Wednesday’s matchup should be another high-scoring affair.

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